abstract：:Twenty-one cases were selected from 236 thyroidectomies with a diagnosis of Hashimoto's disease for detailed clinicopathologic study on the basis of "early" changes in three cases and an unusually heavy lymphoplasmacytic infiltrate in 18 cases. These cases were studied in conjunction with ten cases of high-grade non-H...

journal_title：Human pathology

authors： Hyjek E,Isaacson PG

更新日期：1988-11-01 00:00:00

abstract：:The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue ...

journal_title：Human pathology

authors： Bogomoletz WV,Geboes K,Feydy P,Nasca S,Ectors N,Rigaud C

更新日期：1988-11-01 00:00:00

abstract：:Five cases of persistent neonatal hyperinsulinemic hypoglycemia (PNHH) were studied by a combined immunofluorescent and Feulgen technique under a computerized microscope which was used to measure the area and absorbance of beta cell nuclei. An increase of 16% was found in the nuclear area and absorbance of the beta ce...

journal_title：Human pathology

authors： Ariel I,Kerem E,Schwartz-Arad D,Bartfeld E,Ron N,Pizov G,Zajicek G

更新日期：1988-10-01 00:00:00

abstract：:A 33-year-old male runner, who had undergone a Swanson silastic prosthetic implant for degenerative joint disease of the first metatarsal head and proximal phalanx of the right great toe, presented with unilateral inguinal lymphadenopathy. Biopsy revealed confluent, non-caseating granulomas containing silastic materia...

journal_title：Human pathology

authors： Rogers LA,Longtine JA,Garnick MB,Pinkus GS

更新日期：1988-10-01 00:00:00

abstract：:We reviewed open lung biopsies from 35 patients with Wegener's (pathergic) granulomatosis in order to study the histogenesis of the pulmonary lesions and to identify the early lesions. The process of pathergic necrosis is fundamental in the production of extravascular and vascular lesions and was divided into micronec...

journal_title：Human pathology

authors： Mark EJ,Matsubara O,Tan-Liu NS,Fienberg R

更新日期：1988-09-01 00:00:00

abstract：:Several techniques for diagnosing adenocarcinoma of the lung are commonly available, but the frequency of their use and diagnostic sensitivity may vary. Twenty cases of primary lung adenocarcinoma obtained at surgery were studied by the following four routine techniques: light microscopy (LM) using hematoxylin-eosin (...

journal_title：Human pathology

authors： McGregor DH,Dixon AY,McGregor DK

更新日期：1988-08-01 00:00:00

abstract：:We applied a panel of antibodies to formalin-fixed, paraffin-embedded sections of 55 renal cell carcinomas using a three-stage immunoperoxidase technique. The antibody panel included two anti-keratins, AE1 and CAM5.2, anti-epithelial membrane antigen (EMA), anti-vimentin, anti-S100 protein, and the anti-leukocyte mark...

journal_title：Human pathology

authors： Medeiros LJ,Michie SA,Johnson DE,Warnke RA,Weiss LM

更新日期：1988-08-01 00:00:00

abstract：:One hundred six liver biopsy specimens from 34 orthotopic liver transplant (OLT) patients were examined and the histologic findings correlated with the clinical course of the patients to determine if specific morphologic patterns were associated with specific causes of acute allograft dysfunction. The principle causes...

journal_title：Human pathology

authors： Ray RA,Lewin KJ,Colonna J,Goldstein LI,Busuttil RW

更新日期：1988-07-01 00:00:00

abstract：:Four cases of clear cell lymphoma were studied by means of light and electron microscopy, enzyme-histochemistry, and E- and EAC-rosette formation. On light microscopic examination the tumors were seen to be composed mainly of round, oval, or slight irregular cells with water-clear, abundant cytoplasm. The neoplastic c...

journal_title：Human pathology

authors： Zhuang HG,Liang GZ,Li WC,Zhang YQ,Guo RZ,Liu SL,He NX

更新日期：1988-07-01 00:00:00

abstract：:The histologic findings in lymph nodes were used to identify eight patients, who are not in a high-risk group, with human immunodeficiency virus (HIV) infection. In order to determine the specificity of these findings, the histologic and clinical findings in these patients were compared with the histologic and clinica...

journal_title：Human pathology

authors： Butler JJ,Osborne BM

更新日期：1988-07-01 00:00:00

abstract：:Two hundred three testicular germ cell tumors were studied immunohistochemically for the presence of placental alkaline phosphatase (PLAP). Special emphasis was placed on the pattern and incidence of positive staining of intratubular malignant germ cells (ITMGCs) adjacent to tumors. 99% of cases with adjacent ITMGCs s...

journal_title：Human pathology

authors： Burke AP,Mostofi FK

更新日期：1988-06-01 00:00:00

abstract：:Tissue specimens obtained at autopsy from seven childhood cases of malignant histiocytosis were studied by immunohistochemistry. Clinically, the majority of the cases showed sustained fever, hepatosplenomegaly, pancytopenia, and DIC. The pretreatment diagnosis was based on their typical clinical manifestations and bon...

journal_title：Human pathology

authors： Hibi S,Esumi N,Todo S,Imashuku S

更新日期：1988-06-01 00:00:00

abstract：:Sixteen cases of intermediate lymphocytic lymphoma (ILL), including eight cases with mantle zone architecture, were studied using cryostat sections, a biotin-avidin immunoperoxidase technique, and a large panel of monoclonal antibodies. The neoplastic cells invariably expressed IgM, most B lineage antigens (B1, TO15, ...

journal_title：Human pathology

authors： Strickler JG,Medeiros LJ,Copenhaver CM,Weiss LM,Warnke RA

更新日期：1988-05-01 00:00:00

abstract：:We used light microscopy to examine, at autopsy, bronchial arteries in three patients with cystic fibrosis who died, respectively, 10, 16, and 28 months after bronchial artery embolization with barium sulfate-impregnated polyvinyl alcohol (PVA) to control hemoptysis. PVA was not identified beyond the midsegmental bron...

journal_title：Human pathology

authors： Tomashefski JF Jr,Cohen AM,Doershuk CF

更新日期：1988-05-01 00:00:00

abstract：:The DNA content of both fresh and formalin-fixed, paraffin-embedded tissues from 30 solid neoplasms was analyzed by flow cytometry. Cells from a single paraffin block of each tumor were disaggregated according to the method of Hedley et al. Cells were sampled from multiple sites of each fresh specimen. Fresh and depar...

journal_title：Human pathology

authors： Frierson HF Jr

更新日期：1988-03-01 00:00:00

abstract：:In a review of pediatric autopsies from 1951 to 1985, we identified 40 cases in which pancreatitis was diagnosed pathologically. Twenty-six of these patients were under 4 years of age, and the male-to-female ratio was 1.5. Six groups of patients were identified: 10 with hepatobiliary disease, including 9 with biliary ...

journal_title：Human pathology

authors： Nguyen T,Abramowsky C,Ashenburg C,Rothstein F

更新日期：1988-03-01 00:00:00

abstract：:Most failures of bioprosthetic heart valves in children are due to stenosis secondary to thrombus, calcific deposits, or tissue ingrowth. Valve failures due to regurgitation typically involve cuspal detachment, tears, or perforations. We present four cases of prosthetic valve regurgitation in children caused by cuspal...

journal_title：Human pathology

authors： Murphy SK,Rogler WC,Fleming WH,McManus BM

更新日期：1988-02-01 00:00:00

abstract：:Paraffin-embedded sections of 99 human adrenal and extraadrenal paragangliomas were analyzed by the indirect immunoperoxidase technique for the presence of neuron-specific enolase (NSE) and 10 neuropeptides. Each showed diffuse staining for NSE. Most tumors were positive for [Leu5]-enkephalin (76 per cent), [Met5]-enk...

journal_title：Human pathology

authors： Linnoila RI,Lack EE,Steinberg SM,Keiser HR

更新日期：1988-01-01 00:00:00

abstract：:The relationship between nuclear diameter and biologic behavior was studied in 127 cases of thyroid carcinoma. Using a sonic digitizer coupled to a minicomputer, nuclear diameters of 200 randomly selected cancer cells from each case (hematoxylineosin-stained paraffin sections) projected at X 400 magnification were tra...

journal_title：Human pathology

authors： Lee TK,Myers RT,Bond MG,Marshall RB,Kardon B

更新日期：1987-12-01 00:00:00

abstract：:Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...

journal_title：Human pathology

authors： Ro JY,Silva EG,Gallager HS

更新日期：1987-12-01 00:00:00

abstract：:The synovium in two well-documented cases of alkaptonuric ochronosis was studied by transmission electron and light microscopy. A feature of alkaptonuria previously unreported in the English-language literature was the presence of phagocytosis of large collagen fibrils by synovial macrophages in both cases. The origin...

journal_title：Human pathology

authors： Gaines JJ Jr,Tom GD,Khankhanian N

更新日期：1987-11-01 00:00:00

abstract：:Infiltrating ductal carcinoma of the breast is histologically heterogeneous and may be subdivided into three main types (A, B, and C) which correlate with the likelihood of long-term survival. Examples of each type were tested against three monoclonal antibodies (H59, H71, and H72) prepared against the breast cancer c...

journal_title：Human pathology

authors： Yuan D,Dawson PJ

更新日期：1987-11-01 00:00:00

abstract：:The immunohistologic distribution of the basement membrane components, type IV collagen and laminin, was evaluated in 57 alcohol-fixed, paraffin-embedded tissue sections which demonstrated immunostaining patterns with antigen preservation similar to that of frozen tissue sections. Normal and hyperplastic squamous muco...

journal_title：Human pathology

authors： Sakr WA,Zarbo RJ,Jacobs JR,Crissman JD

更新日期：1987-10-01 00:00:00

abstract：:Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a pa...

journal_title：Human pathology

authors： Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BA

更新日期：1987-10-01 00:00:00

abstract：:The small, variously designated, primary atrioventricular node tumor has been considered to be of endothelial, endodermal, or mesothelial origin. To identify its derivation, we studied seven tumors using silver staining and immunocytochemical labeling with a variety of antibodies. Cytoplasmic argyrophil granules but n...

journal_title：Human pathology

authors： Fine G,Raju U

更新日期：1987-08-01 00:00:00

abstract：:A case of recurrent Hodgkin's disease of the "sarcomatoid" or "syncytial variant" type was seen that occurred as an extension from the mediastinum to a previously uninvolved extranodal site (breast) and pericardium after treatment of classical nodular sclerosing Hodgkin's disease based in the lymph nodes. This histolo...

journal_title：Human pathology

authors： Blaustein JC,Lewkow L

更新日期：1987-07-01 00:00:00

abstract：:Thromboangiitis obliterans (Buerger's disease) is an uncommon variety of occlusive peripheral vascular disease, occurring predominantly in young male tobacco smokers. The vascular lesion in the acute stage of thromboangiitis obliterans is distinctive and affects both the arteries and veins. Described here is an unusua...

journal_title：Human pathology

authors： Lie JT

更新日期：1987-04-01 00:00:00

abstract：:Focal apocrine metaplasia was studied in 293 whole human breasts by a subgross sampling technique with histologic confirmation. There were 186 breasts obtained from random autopsies. Another 107 breasts were obtained that were cancer-associated; these breasts either contained an invasive cancer or were situated contra...

journal_title：Human pathology

authors： Wellings SR,Alpers CE

更新日期：1987-04-01 00:00:00

abstract：:A distinctive ultrastructural finding, observed in a case of acute lymphoblastic leukemia (ALL) and previously unreported on the surface of bone marrow cells, is described. The alteration is referred to as distinctive cytoplasmic surface activity (DCSA). For further delineation, study of 130 consecutively submitted bo...

journal_title：Human pathology

authors： de Chadarévian JP,Corriveau M

更新日期：1987-04-01 00:00:00

abstract：:The pathology of cytomegalovirus (CMV) encephalitis was studied at autopsy in thirty patients with acquired immunodeficiency syndrome. Lesions could be segregated into five major categories: microglial nodules, isolated inclusion-bearing cells, focal parenchymal necrosis, necrotizing ventriculo-encephalitis, and necro...

journal_title：Human pathology

authors： Morgello S,Cho ES,Nielsen S,Devinsky O,Petito CK

更新日期：1987-03-01 00:00:00

abstract：:Platelet stimulus-activation-contraction-secretion coupling is linked to fundamental modifications in the biochemistry and ultrastructure of the platelet surface and the membranes enclosing storage organelles. It is not surprising, therefore, that membrane defects are common in platelets from patients with inherited h...

journal_title：Human pathology

authors： White JG

更新日期：1987-02-01 00:00:00

abstract：:A membrane-bound, Ca2-dependent complex of the cofactor factor Va and the enzyme factor Xa comprises the prothrombinase coagulation complex, which catalyzes the proteolytic conversion of prothrombin to thrombin. In normal hemostasis, the platelet is presumed to supply the surface membrane and thus constitutes the site...

journal_title：Human pathology

authors： Tracy PB,Mann KG

更新日期：1987-02-01 00:00:00

abstract：:Because infants rarely suffer coronary artery thrombosis, it is mistakenly assumed that they seldom have significant ischemic myocardial injury. However, ischemic myocardial necrosis (INM) is common in the papillary muscles and subendocardium of stressed newborns and other infants. Standard dissection methods encourag...

journal_title：Human pathology

authors： Donnelly WH,Hawkins H

更新日期：1987-01-01 00:00:00

abstract：:A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. Thi...

journal_title：Human pathology

authors： Honda N,Cobb C,Lechago J

更新日期：1986-12-01 00:00:00

abstract：:In a series of approximately 80,000 lymph nodes, amyloid deposition was found in 18; 12 of those nodes were selected, on the basis of availability of specimens, for investigation by immunohistochemical typing to identify the protein of origin and by correlation with morphologic criteria and clinical information. Four ...

journal_title：Human pathology

authors： Newland JR,Linke RP,Lennert K

更新日期：1986-12-01 00:00:00

abstract：:Twenty-five cases of Crohn's disease confined to the appendix were reported in eight hospitals in Israel during a 15-year period. Review of the histologic slides confirmed the diagnosis in 22 cases. Re-evaluation of these 22 patients included physical examination and radiologic studies of the small and large bowel. Re...

journal_title：Human pathology

authors： Ariel I,Vinograd I,Hershlag A,Olsha O,Argov S,Klausner JM,Rabau MY,Freund U,Rosenmann E

更新日期：1986-11-01 00:00:00

abstract：:In an attempt to identify patients best suited for limited surgery as well as those at risk for recurrence and increased mortality, the authors reviewed the clinical and pathologic features of 130 patients who had undergone partial mastectomy as primary treatment for breast cancer (adjuvant therapy was administered on...

journal_title：Human pathology

authors： Lash RH,Bauer TW,Hermann RE,Esselstyn CB

更新日期：1986-08-01 00:00:00

abstract：:Fourteen chordomas, five myxoid chondrosarcomas, and 15 chondroid tumors (four mesenchymal and 11 conventional chondrosarcomas) were stained for cytokeratin, S-100 protein, carcinoembryonic antigen (CEA), and vimentin. The epithelial markers stained 93 per cent of the chordomas, whereas none of the tumors of other typ...

journal_title：Human pathology

authors： Abenoza P,Sibley RK

更新日期：1986-07-01 00:00:00

abstract：:In the past decade most studies of coronary arterial aneurysms have been clinical; few have focused on morphology and etiopathogenesis. The subjects of the present autopsy study were 52 patients, 5 months to 80 years of age, with coronary arterial aneurysms. Patients were divided into two groups: 38 with atherosclerot...

journal_title：Human pathology

authors： Virmani R,Robinowitz M,Atkinson JB,Forman MB,Silver MD,McAllister HA

更新日期：1986-06-01 00:00:00

abstract：:Fifty-three surgically resected small cell carcinomas of the lung were studied morphometrically, electron microscopically, immunohistochemically, and in terms of possible site of origin. Four subtypes of small cell carcinomas were identified: oat cell carcinoma (OAT), small cell carcinoma of the intermediate cell type...

journal_title：Human pathology

authors： Nomori H,Shimosato Y,Kodama T,Morinaga S,Nakajima T,Watanabe S

更新日期：1986-06-01 00:00:00